Strattons nightclub closed in 2012 and Results gym moved into part of the space.
For decades, clubbers enjoyed heading to the club – known in the town as ‘Stickies’.
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From the early 1990s it was called Themes, Buddies, Strattons and then very briefly Funky Monkeys, before shutting for good in 2012.
Now, KAT Enterprises Abingdon No2 Limited has submitted a premises licence application to Vale of White Horse District Council.
The application is for a new licence for Coxeter House, the home of Results gym, for regulated entertainment, late night refreshment and the sale of alcohol.
Anyone wanting to give their views was asked to contact the council by September 12.
One former club goer said on Facebook in 2020: “Oh yes, so many memories of this place. Thursday night a pound a pint of snakebite and black.
“Almost always a fight involving the army lads. Happy days.”
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“Another said: “Bring it back! Probably had more of a workout in there as a club than a gym.”
One clubber added: “Watched Buster Bloodvessel there in the early 90s.”
Another said: “It was Themes when I first went there. Great Thursday night’s out with good friends.”
In 2008, Strattons had tougher conditions put on its licence, including drinks promotions not being allowed from Thursdays to Sundays.
Andrew Fudge, who is leading the plans, has said on Facebook that the new venue will not be a nightclub. He has been asked to comment further.
A cafe has recently been operating on the ground floor but it now appears to be shut with some building work taking place.
In 2017, Coxeter House has persuaded a private firm to drop more than 1,500 penalty charges and dozens of court cases against drivers who used its car park – claiming it was hassling people who were eligible to park there.
The cluster of buildings in Stratton Way accommodate businesses including the gym and shops, whose staff and customers can use the 50 parking spaces.
Coxeter family members have been prominent traders in Abingdon throughout the 19th and 20th centuries, and owned numerous shops in Ock Street.
According to the town council, During the first half of the 20th century, Coxeters continued in its core trade of hardware and furnishing.
It reorganised itself in 1951, becoming a limited company and later opening Coxeter House as a department store.
In 1984 it ceased to trade as a retailer, concentrating on property management and finance.
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Andy is the Trade and Tourism reporter for the Oxford Mail and you can sign up to his newsletters for free here.
He joined the team more than 20 years ago and he covers community news across Oxfordshire.
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