Looking for the best against-the-spread bet among all 16 NFL matchups in Week 8? Our choice, in terms of ATS, is Commanders +1.5. But scroll down, because we have lots more suggestions, and that could lead to parlay opportunities.

NFL Picks Against the Spread – Week 8

Jump to Matchup:

Pick: Commanders +1.5 vs. Bears

• Matchup: Chicago Bears at Washington Commanders
• Projected Winner & Margin: Commanders by 9.1 points (Bet on this game at BetMGM)
• Spread: Bears -1.5
• Time: 4:25 p.m. ET
• Date: Oct. 27
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Buccaneers +2.5 vs. Falcons

• Matchup: Atlanta Falcons at Tampa Bay Buccaneers
• Projected Winner & Margin: Buccaneers by 13.8 points (Bet on this game at BetMGM)
• Spread: Falcons -2.5
• Time: 1 p.m. ET
• Date: Oct. 27
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Eagles +2.5 vs. Bengals

• Matchup: Philadelphia Eagles at Cincinnati Bengals
• Projected Winner & Margin: Eagles by 4.5 points (Bet on this game at BetMGM)
• Spread: Bengals -2.5
• Time: 1 p.m. ET
• Date: Oct. 27
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Vikings -3 vs. Rams

• Matchup: Minnesota Vikings at Los Angeles Rams
• Projected Winner & Margin: Vikings by 9.8 points (Bet on this game at BetMGM)
• Spread: Vikings -3
• Time: 8:15 p.m. ET
• Date: Oct. 24
• TV Channel: Amazon Prime Video
• Live Stream: Watch this game on Prime Video (Regional restrictions may apply)

Pick: Cardinals +3 vs. Dolphins

• Matchup: Arizona Cardinals at Miami Dolphins
• Projected Winner & Margin: Cardinals by 12.9 points (Bet on this game at BetMGM)
• Spread: Dolphins -3
• Time: 1 p.m. ET
• Date: Oct. 27
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Seahawks +3 vs. Bills

• Matchup: Buffalo Bills at Seattle Seahawks
• Projected Winner & Margin: Bills by 2.7 points (Bet on this game at BetMGM)
• Spread: Bills -3
• Time: 4:05 p.m. ET
• Date: Oct. 27
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Packers -4.5 vs. Jaguars

• Matchup: Green Bay Packers at Jacksonville Jaguars
• Projected Winner & Margin: Packers by 16.5 points (Bet on this game at BetMGM)
• Spread: Packers -4.5
• Time: 1 p.m. ET
• Date: Oct. 27
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: 49ers -4.5 vs. Cowboys

• Matchup: Dallas Cowboys at San Francisco 49ers
• Projected Winner & Margin: 49ers by 9.2 points (Bet on this game at BetMGM)
• Spread: 49ers -4.5
• Time: 8:20 p.m. ET
• Date: Oct. 27
• TV Channel: NBC
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Texans -6 vs. Colts

• Matchup: Indianapolis Colts at Houston Texans
• Projected Winner & Margin: Texans by 7.5 points (Bet on this game at BetMGM)
• Spread: Texans -6
• Time: 1 p.m. ET
• Date: Oct. 27
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Steelers -6.5 vs. Giants

• Matchup: New York Giants at Pittsburgh Steelers
• Projected Winner & Margin: Steelers by 18.9 points (Bet on this game at BetMGM)
• Spread: Steelers -6.5
• Time: 8:15 p.m. ET
• Date: Oct. 28
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Jets -7 vs. Patriots

• Matchup: New York Jets at New England Patriots
• Projected Winner & Margin: Jets by 9.0 points (Bet on this game at BetMGM)
• Spread: Jets -7
• Time: 1 p.m. ET
• Date: Oct. 27
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Chargers -7.5 vs. Saints

• Matchup: New Orleans Saints at Los Angeles Chargers
• Projected Winner & Margin: Chargers by 9.9 points (Bet on this game at BetMGM)
• Spread: Chargers -7.5
• Time: 4:05 p.m. ET
• Date: Oct. 27
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Pick: Broncos -8.5 vs. Panthers

• Matchup: Carolina Panthers at Denver Broncos
• Projected Winner & Margin: Broncos by 28.5 points (Bet on this game at BetMGM)
• Spread: Broncos -8.5
• Time: 4:25 p.m. ET
• Date: Oct. 27
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Ravens -9 vs. Browns

• Matchup: Baltimore Ravens at Cleveland Browns
• Projected Winner & Margin: Ravens by 18.4 points (Bet on this game at BetMGM)
• Spread: Ravens -9
• Time: 1 p.m. ET
• Date: Oct. 27
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Chiefs -10 vs. Raiders

• Matchup: Kansas City Chiefs at Las Vegas Raiders
• Projected Winner & Margin: Chiefs by 16.2 points (Bet on this game at BetMGM)
• Spread: Chiefs -10
• Time: 4:25 p.m. ET
• Date: Oct. 27
• TV Channel: CBS
• Live Stream: Paramount+ | Fubo (Regional restrictions may apply)

Pick: Lions -11 vs. Titans

• Matchup: Tennessee Titans at Detroit Lions
• Projected Winner & Margin: Lions by 22.9 points (Bet on this game at BetMGM)
• Spread: Lions -11
• Time: 1 p.m. ET
• Date: Oct. 27
• TV Channel: FOX
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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