Nukewatchers from Campaign for Nuclear Disarmament (CND), who monitor and track these convoys, said the convoy consisted of four warhead carriers, MOD escort and support vehicles.
They said it left Atomic Weapons Establishment (AWE) Burghfield in Berkshire early Monday (October 21) morning and travelled north through Oxfordshire.
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A picture sent to the Oxford Mail shows the convoy travelling northbound on the A34 between Kidlington and Oxford at 10.50am.
The group believed the convoy was heading for Royal Naval Armament Depot Coulport, near the Faslane nuclear submarine base in Scotland.
Nukewatch is a network of individuals who campaign against nuclear warhead convoys, relying on members of the public to inform them of sightings.