Oxford have won just one of their last 10 games (D5 L4) following a 1-0 defeat at Watford last time out and welcome a Middlesbrough side who thrashed Luton 5-1 before the international break.
The U’s are two points above the drop zone, while Boro are just one point behind Watford in the play-off spots and have won two on the bounce, scoring nine goals in the process.
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Oxford United have failed to win any of their last eight league games against Middlesbrough (D2 L6), though this is the first such meeting since a 4-1 loss in May 1998.
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Middlesbrough are unbeaten across their last four away league games against Oxford United (W3 D1), winning their last visit 4-1 in October 1997.
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Oxford United won three of their opening five Championship games this season (L2) but have since won just one of their last 10 games (D5 L4).
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Middlesbrough have had the second-most shots in the Championship this season (242), while opponents Oxford have had the fewest (148).
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Boro have netted 4+ goals in their last two games (4-1 v QPR, 5-1 v Luton) and last did so in three in a row back in November 1947.