OXFORD, Miss. (AP) — Skylar Vann scored a career-high 24 points, Sahara Williams had a double-double and Oklahoma upended No. 12 Mississippi 80-70 on Thursday night.

Behind Vann, the only player to win Big 12 Conference Sixth Player of the Year twice, the Sooners took charge by scoring the last six points of the third quarter and the first four of the fourth for a 66-57 lead.

Ole Miss (1-1) got within five but the No. 23 Sooners (2-0) pulled away again. Vann hit a 3-pointer and followed it up with a three-point play on the next possession before her layup made it 80-66 with 1:43 to play.

Williams had 13 points and 10 rebounds and Lexy Keys added 11 points. Oklahoma had 21 assists on 28 baskets and went 20 of 23 from the foul line. The Sooners picked up their first true road win over a ranked nonconference opponent since 2007, a skid of 16 games

Snudda Collins had 15 points and North Carolina transfer Kennedy Todd-Williams had 13 as the Rebels put five players in double figures.

Ole Miss led 18-17 after one quarter and 39-38 at the half. Oklahoma’s surge to the lead at the end of the third quarter was the last of 13 lead changes. The Rebels were just 5 of 19 from the field in the last 10 minutes.

The Sooners return to Norman on Sunday for a 2 p.m. matchup vs. Oral Roberts (1-1) at Lloyd Noble Center.