The U’s raced into a three-goal advantage by half-time, and took the lead with quarter of an hour on the clock.
Jenna Legg made her way down the wing before cutting in and finding the back of the net.
Three minutes later, Kate Wiseman struck a free kick over the wall, with her effort smacking the crossbar.
Sarah King’s rocket from the edge of the penalty area put United two goals up after 24 minutes, while the third goal was added six minutes before the break.
Adele Lindbaek skipped past a couple of players and then found Phoebie Poole, who ran into the box and applied the finish.
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Just after the hour mark, the U’s worked the ball forward to Lucy Trinder, who strode down the wing and slotted home.
Trinder made it a brace with two minutes to go, burying an effort from inside the six-yard box.
United manager Sam Rose said: “I’m really pleased. Lots of different goalscorers and minutes in the legs for players that needed it, and a clean sheet.
“I thought we played some really good football. Credit to the opposition, it could’ve been more, but the goalkeeper’s made some really good saves and kept the scoreline that little bit closer.”
The U’s, second in Southern Premier Division, are next in action on Sunday afternoon, when they make the trip to league leaders Hashtag United.